If they ever implement the explanation in an NPC, it should not be skipable the first time as Zipp said.. (what about placing an NPC next to the door of the daycare in isle 4? or next to the old man?)
Whether they change the mechanics or not, information about it would be greatly appreciated in the in-game FAQ, it does get tiring to do a long explanation on global everytime the questions pops up (mind you, more than just a few times per day), in the end if you're tired you simply tell them to go to cinnabar lab.. but it would be great to be able to say "Press H and read the faq handsome [user name]" or "Talk to the NPC next to the daycare"